Who and Why do Patients Report Lymphedema After Breast Cancer Treatment Without an Objective Measurable Swelling

NARecruitingINTERVENTIONAL
Enrollment

230

Participants

Timeline

Start Date

March 26, 2024

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2027

Conditions
Breast CancerLymphedemaSensory Processing Disorder
Interventions
OTHER

Measurements for breast cancer related lymphedema (volumetric measurements, bioimpedance spectroscopy, bioimpedance analysis, tissue dielectric constant measurements, ultrasonography)

"Assessments related to different types of breast cancer related lymphedema at arm (1. self-reported swelling at arm, 2. subjective arm lymphedema, 3. objective arm lymphedema) using the Norman questionnaire, volume measurements (volumetry and perimetry), bioimpedance spectroscopy, and bioimpedance analysis~Assessments related to different types of breast cancer related lymphedema at trunk/ breast (1. self-reported swelling at trunk/ breast, 2. subjective trunk/ breast lymphedema, 3. objective trunk/ breast lymphedema) using the Norman questionnaire, tissue dielectric measurements, and ultrasonography"

OTHER

Measurements for lymphatic problems (volumetric measurements, tissue dielectric measurement, lymphofluoroscopy)

Clinical assessments related to lymphatic problems (1. amount of swelling at arm by relative arm volume difference, 2. amount of swelling at trunk by percentage water ratio, 3. severity of dermal rerouting at upper limb and trunk by lymphofluoroscopy (i.e., near-infrared fluorescence imaging device)

OTHER

Measurements for sensory processing problems by monofilaments, algometer, goniometer, and neurosensory analyzer

Clinical measurements related to nociceptive, neuropathic and central sensory problems based on the Quantitative Sensory Testing principles using different devices algometer, goniometer, standardized set of monofilaments, and neurosensory analyzer

Trial Locations (1)

3000

RECRUITING

University Hospitals of Leuven, center for lymphedema, Leuven

All Listed Sponsors
collaborator

Universiteit Antwerpen

OTHER

lead

Universitaire Ziekenhuizen KU Leuven

OTHER