Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

NANot yet recruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

March 18, 2024

Primary Completion Date

March 18, 2025

Study Completion Date

March 18, 2026

Conditions
Bladder Cancer
Interventions
PROCEDURE

Transurethral cryoablation

Using an intracavitary cryoablation balloon, cryoablation is performed on the wound surface after tumor resection. The wound surface is frozen for 2 rounds, with each round lasting 3 minutes, to fully cover the wound surface.

PROCEDURE

Transurethral resection of bladder tumor

Resection of bladder tumor using resectoscopy, which is a standard procedure to treat non-muscle invasive bladder cancer

DRUG

Bcg Intravesical

Bacillus Calmette-Guerin instillation of bladder after surgery according to the NCCN bladder cancer guidelines. At least 6 weeks induction instillation is required for high-risk NMIBC patients. At least 1 year maintenance instillation is recommended.

All Listed Sponsors
lead

Huashan Hospital

OTHER

NCT06324058 - Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC | Biotech Hunter | Biotech Hunter