Lymphedema Duration on Lymphatic Vessel Quality and Outcomes After LVA

CompletedOBSERVATIONAL
Enrollment

189

Participants

Timeline

Start Date

September 30, 2015

Primary Completion Date

March 31, 2023

Study Completion Date

March 31, 2023

Conditions
Lymphedema
Interventions
PROCEDURE

lymphaticovenous anastomosis

The patients were under intravenous general anesthesia with local anesthetic infiltration for each incision21. LVs were detected by intradermal injection of ICG into the web spaces between the toes and on the medial and lateral malleoli. ICG flow with linear dermal backflow(DB) patterns was detected immediately using a handheld near-infrared camera. The recipient veins were marked using B-mode echo Doppler, close to the marked linear pattern. In case of DB pattern, the incision was made along the great saphenous vein. A 3 cm incision was made and the lymphatics and recipient veins were identified. All patients underwent supermicrosurgical LVA with 11- 0 nylon sutures using a high-power surgical microscope by a single senior surgeon. LVAs are performed using only antegrade flow lymphatics and lymphaticovenous end-to-end anastomosis (LVEEA) and end-to-side anastomosis (LVESA).

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER

NCT06323200 - Lymphedema Duration on Lymphatic Vessel Quality and Outcomes After LVA | Biotech Hunter | Biotech Hunter