Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

RecruitingOBSERVATIONAL
Enrollment

240

Participants

Timeline

Start Date

June 15, 2023

Primary Completion Date

December 15, 2024

Study Completion Date

July 15, 2025

Conditions
Motor Neuron Disease, Amyotrophic Lateral SclerosisMotor Neuron Disease Progressive Spinal Muscle AtrophyPrimary Lateral SclerosisMultiple SclerosisPostpoliomyelitis Syndrome
Interventions
PROCEDURE

232 Electrode Electrophysiology (EEG-ECG-EMG-EXG)

"Noninvasive 232 Channel Electrode Electrophysiological signals (EEG-ECG-EMG-EXG) will be recorded from electrodes placed in a montage over the scalp, neck,and upper back along with muscles located on the hand. These signals will be recorded while resting or performing voluntary task.~Other Intervention: The 232 electrode noninvasive electrophysiological data will be recorded in response to non-invasive peripheral nerve stimulation or vibration induced stimulation.~These sessions are designed to engage specific cortical motor networks of interest for evaluating sensorimotor networks. (Cognitive, behavioural, motor, spinal, and sensory)"

Trial Locations (1)

Dublin 2

RECRUITING

Academic Unit of Neurology, Trinity College Dublin, The University of Dublin, Dublin

All Listed Sponsors
collaborator

Motor Neurone Disease Association, UK

UNKNOWN

collaborator

Irish Research Council, IE

UNKNOWN

collaborator

Health Research Board, IE

UNKNOWN

collaborator

Research Motor Neurone, IE

UNKNOWN

collaborator

Thierry Latran Foundation, FR

UNKNOWN

collaborator

ALS Association, USA

UNKNOWN

lead

University of Dublin, Trinity College

OTHER