Emergency Medicine Pulmonary Embolism Testing Multicentre Study

RecruitingOBSERVATIONAL
Enrollment

4,000

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2027

Conditions
Pulmonary EmbolismD-dimerDiagnosis
Interventions
DIAGNOSTIC_TEST

Adjust-Unlikely

"Pulmonary embolism will be excluded during emergency department assessment by the combination of:~1. 'Pulmonary embolism is the most likely diagnosis' as per the treating physician AND a D-dimer result \< 500 ug/L fibrinogen equivalent units;~2. 'Pulmonary embolism is not the most likely diagnosis' AND D-dimer \< age-adjusted threshold; or,~3. A negative computed tomography scan, planar ventilation perfusion scan or ventilation perfusion-SPECT.~Emergency departments will use their local laboratory D-dimer assay."

Trial Locations (1)

K7L 2V7

RECRUITING

Kingston Health Sciences Centre, Kingston

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

lead

Dr. Kerstin de Wit

OTHER