3,513
Participants
Start Date
January 1, 2024
Primary Completion Date
October 31, 2024
Study Completion Date
December 31, 2024
Evaluating ASCVD risk over 10 and 30 year and lifetime
Utilizing validated tools such as the Pooled Cohort Equations (PCE) for 10-year ASCVD risk, the 30-year ASCVD risk prediction tool, and lifetime ASCVD risk categories, participants will undergo a thorough risk assessment. This multi-dimensional approach ensures a nuanced understanding of short and long-term cardiovascular risks. Further, The genetic risk for ApoB will be meticulously assessed by genotyping the APOB rs1042031 variant. Subsequently, the calculation of the genetic risk score (GRS) based on risk alleles will provide personalized insight into genetic predispositions related to ASCVD risk. Moreover, Participants will receive personalized management recommendations derived from the ACC/AHA Cardiovascular Risk Assessment Guidelines. These tailored suggestions may encompass dietary programs, lifestyle modifications, and, when indicated, pharmaceutical therapies like statins, aiming to mitigate identified risks effectively
RECRUITING
Advanced Education Institute and Research Center, Karachi
Lead Sponsor
University of Karachi
OTHER
Pakistan Cardiac Society (Heart House)
UNKNOWN
Advanced Education & Research Center
OTHER