The Anticariogenic Effect of Silver Diamine Fluoride and Sodium Fluoride Varnish

PHASE1CompletedINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

September 29, 2023

Study Completion Date

January 26, 2024

Conditions
Early Childhood Caries
Interventions
DRUG

Silver diamine fluoride

38% Silver Diamine Fluoride (SDF) is a topical antimicrobial and remineralizing agent which was cleared by the FDA as a Class II medical device to treat tooth sensitivity. In certain circumstances, SDF may be used as a non-restorative treatment to arrest carious lesions on primary and permanent teeth

DRUG

Sodium fluoride

Fluoride varnish to apply on tooth surface, so that the tooth becomes more resistant to caries attack. The active ingredient of fluoride varnish is 5% sodium fluoride, (22,600 ppm fluoride)

Trial Locations (1)

47000

University Technology MARA, Sungai Buloh

All Listed Sponsors
lead

Universiti Teknologi Mara

OTHER