A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

375

Participants

Timeline

Start Date

March 16, 2024

Primary Completion Date

December 1, 2026

Study Completion Date

December 1, 2026

Conditions
Locally Advanced Rectal Carcinoma
Interventions
DRUG

Tislelizumab

Enrolled patients will receive tislelizumab 3 times after initiation of radiotherapy.

Trial Locations (2)

100050

RECRUITING

Beijing Friendship Hospital, Capital Medical University, Beijing

RECRUITING

Beijing Friendship Hospital, Beijing

All Listed Sponsors
collaborator

Beijing Chao Yang Hospital

OTHER

collaborator

Peking University Cancer Hospital & Institute

OTHER

collaborator

China-Japan Friendship Hospital

OTHER

collaborator

Peking Union Medical College Hospital

OTHER

collaborator

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER

collaborator

Fudan University

OTHER

collaborator

Changhai Hospital

OTHER

collaborator

RenJi Hospital

OTHER

collaborator

Sir Run Run Shaw Hospital

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Zhongnan Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Sichuan Academy of Medical Sciences

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

collaborator

The First Hospital of Jilin University

OTHER

collaborator

First Hospital of China Medical University

OTHER

collaborator

Xijing Hospital of Airforce Medical University

UNKNOWN

collaborator

Tangdu Hospital-Air Force Medical University

UNKNOWN

collaborator

The Affiliated Hospital of Qingdao University

OTHER

collaborator

Daping Hospital, the Third Military Medical University

UNKNOWN

collaborator

Tianjin Union Medical Center

OTHER

collaborator

The First Affiliated Hospital of Shanxi Medical University

OTHER

collaborator

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

collaborator

The Affiliated Tumour Hospital of China Academy of Medical Science

UNKNOWN

collaborator

Rocket Force Characteristic Medical Center

UNKNOWN

collaborator

Tianjin Medical University General Hospital

OTHER

collaborator

The Second Affiliated Hospital of Naval Medical University

UNKNOWN

collaborator

West China Hospital

OTHER

collaborator

Southern Medical University - Southern Hospital

UNKNOWN

collaborator

First Affiliated Hospital of Chongqing Medical University

OTHER

collaborator

The First Affiliated Hospital of Anhui Medical University

OTHER

collaborator

Hebei Medical University Fourth Hospital

OTHER

collaborator

Sun Yat-sen University

OTHER

collaborator

Zhejiang Tumor Hospital

OTHER

collaborator

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

UNKNOWN

collaborator

Beijing Hospital of the Ministry of Health

UNKNOWN

collaborator

Queen Mary Hospital, Hong Kong

OTHER

collaborator

The University of Hong Kong-Shenzhen Hospital

OTHER

collaborator

Taiwan Hexin Cancer Center Hospital

UNKNOWN

collaborator

First Affiliated Hospital of Wenzhou Medical University

OTHER

lead

Beijing Friendship Hospital

OTHER