Novel Approaches for Improving Vascular Function in Veterans With HFpEF

PHASE1RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

May 19, 2021

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2030

Conditions
Heart Failure With Preserved Ejection FractionInflammation
Interventions
DRUG

L-Citrulline

100 mg tablet

DRUG

Placebo for L-Citrulline

L-Citrulline-matched Placebo tablet

DRUG

BH4

10mg/kg

DRUG

Placebo for BH4

BH4-matched Placebo

DRUG

Atorvastatin

10 mg tablet

DRUG

Placebo for Atorvastatin

Atorvastatin-matched Placebo

Trial Locations (1)

84148-0001

RECRUITING

VA Salt Lake City Health Care System, Salt Lake City, UT, Salt Lake City

All Listed Sponsors
collaborator

University of Utah

OTHER

lead

VA Office of Research and Development

FED

NCT06312748 - Novel Approaches for Improving Vascular Function in Veterans With HFpEF | Biotech Hunter | Biotech Hunter