Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness

Immediate descent from altitude for severe symptoms or anyone who wished to discontinue their participation in the study.

Diphenhydramine was available to counteract any potential extrapyramidal side effects of the study drug. The use of Diphenhydramine for this purpose is well established.

Subjects in the Prochlorperazine arm were administered 10mg PO Prochlorperazine immediately prior to ascent