NCT06310018 - Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions

Pulmonary EmbolismRight Ventricular DysfunctionRight Ventricular Failure

Interventions

DEVICE

Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis

Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis (treated with a total dose 8 mg tPA given as 2 mg/hour/catheter over 2 hours for first 10 patients followed by 50 patients treated with total dose 6 mg tPA given as 3 mg/hour/catheter given over 1 hour) with the EKOS+™ system