Hyaluronic Acid and Polynucleotides for Supra-bony Defects

NARecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

October 21, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Periodontal DiseasesWound HealPeriodontal InflammationPeriodontal PocketPeriodontal Attachment Loss
Interventions
COMBINATION_PRODUCT

Periodontal Access Flap (AF) + Combined Formulation of Hyaluronic acid and Polydeoxyribonucleotides (PNHA)

A conservative access flap will be performed such as simplified papilla preservation flap (SPPF). A PNHA gel will be placed on the root surfaces and supra-bony defects, followed by a tension-free primary closure of the interdental papillae and of the mucoperiosteal flaps by means of 5-0 suture

PROCEDURE

Periodontal Access Flap (AF)

A conservative access flap will be performed such as simplified papilla preservation flap (SPPF). No gel will be placed before suturing the flap by tension-free primary closure of the interdental papillae and of the mucoperiosteal flaps by means of 5-0 suture

Trial Locations (2)

E1 1BB

RECRUITING

Barts Health NHS Trust Dental Hospital, London

E1 2AD

RECRUITING

Centre for Oral Clinical Research (COCR), London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Geistlich Pharma AG

INDUSTRY

lead

Queen Mary University of London

OTHER