Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients

NARecruitingINTERVENTIONAL
Enrollment

88

Participants

Timeline

Start Date

April 1, 2024

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Prostate CancerUrinary Bladder CancerSurgeryPositive End Expiratory PressureLung Ultrasound
Interventions
PROCEDURE

Lung Ultrasound - guided Stepwise PEEP

After endo-tracheal intubation; A PEEP of 4 cmH2O will be initially used till 5 min after pneumoperitoneum. Then The PEEP will be adjusted in a stepwise approach after performing bedside lung ultrasound. The PEEP will be increased by 2 cmH2O until no lung collapse is detected. Lung ultrasound will be repeated 5 min after every change in the PEEP with a maximal PEEP of 12 cmH2O.

PROCEDURE

Standard Ventilation Protocol

Volume-controlled ventilation (VCV) mode; with a tidal volume of 6 mL/kg of ideal weight, inspiratory : expiratory ratio 1: 2, PEEP 4 cmH2O, respiratory rate adjusted to keep end-tidal carbon dioxide tension (EtCO2) between 35 and 40 mm Hg, and inspired oxygen fraction of 50%.

Trial Locations (1)

Unknown

RECRUITING

Cairo University Hospitals, Cairo

All Listed Sponsors
lead

Nazmy Edward Seif

OTHER