Ultrasound Guided Recruitment Manauvere Versus Individualized Positive End Expiratory Pressure in Pediatric Patients Undergoing Laparoscopic Abdominal Surgery

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 12, 2024

Primary Completion Date

August 1, 2024

Study Completion Date

August 1, 2024

Conditions
Ultrasound Guided Recruitment ManauvereEnd Expiratory PressurePediatric PatientsLaparoscopic Abdominal Surgery
Interventions
OTHER

Fixed PEEP

Patients will receive a fixed positive end-expiratory pressure (PEEP) of 5 cmH2O throughout the surgical procedure.

OTHER

Ultrasound-guided lung recruitment

Patients will receive ultrasound-guided lung before pneumoperitoneum, after pneumoperitoneum then once an hour, until the end of surgery. Alveolar recruitment will be conducted the same as that for the conventional manoeuvre with a simultaneous continuous ultrasound assessment if atalectasis is detected until no collapsed areas are visualized. When the collapsed lung areas are absent on the sonogram, positive end-expiratory pressure (PEEP) can no longer increase at this point. Subsequently, the pressure will be maintained for approximately 10 breaths.

OTHER

Individualized PEEP

Patients will receive individualized positive end-expiratory pressure (PEEP). After the first recruitment Maneuvere (RM), titration of PEEP will be performed by setting the initial PEEP to 5 cm H2O, then increasing PEEP according to the gradient of 2 cmH2O every 3 min, calculating static compliance (Cstat) according to the formula: \[Cstat = VT/Pplat - PEEP\] (Pplat = plateau pressure), then gradually increasing PEEP, until the calculated Cstat shows a downward trend, the we set its previous PEEP (corresponding to PEEP for high Cstat) as the optimal PEEP for this patient. The highest PEEP is limited to 15 cmH2O.

Trial Locations (1)

31527

RECRUITING

Tanta University, Tanta

All Listed Sponsors
lead

Tanta University

OTHER