Biomarkers in Retinitis Pigmentosa

RecruitingOBSERVATIONAL
Enrollment

35

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

April 30, 2025

Study Completion Date

April 30, 2025

Conditions
Retinitis Pigmentosa
Interventions
DIAGNOSTIC_TEST

OCT, OCT angiography, flicker ERG and Ultra Wide Field retinography and autofluorescence.

"the best visual acuity will be evaluated using decimal tables and then converted to logMar.~Ocular fundus examination will be evaluated following pharmacological mydriasis with Tropicamide 1%.~OCT will be essential to quantify the central macular thickness and the thickness of the RPE.~OCT angiography is a non-invasive method to assess the presence or absence of neovascular membrane and macular flow density.~Color and ultra wide field autofluorescence images of the retina will be performed with Zeiss Clarus retinography to search for signs that identify different types of RP and predict their activity and evolution.~Electroretinogram flicker (ERG) is a common measure of cone pathway function that is used to study the normal visual system and that of patients with inherited and acquired retinal dysfunction Measurements will be performed using an electrophysiological recording system (CSO). Intermittent stimuli are presented using a Ganzfeld dome (CSO)."

Trial Locations (1)

00198

RECRUITING

Maria Cristina Savastano, Roma

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER