546
Participants
Start Date
June 30, 2025
Primary Completion Date
December 31, 2027
Study Completion Date
June 30, 2028
Acetaminophen and Vitamin C with Naproxen rescue
"900 mg vitamin C taken orally twice a day (one in the morning and one in the evening) for a 7-day period after ED discharge for the treatment arm used in combination with extended-release acetaminophen 650 mg two pills every eight hours regularly.~Naproxen 500mg as rescue medication if still in pain 60 minutes after treatment with acetaminophen."
Acetaminophen and Placebo with Naproxen rescue
"Placebo taken orally twice a day (one in the morning and one in the evening) for a 7-day period after ED discharge for the treatment arm used in combination with extended-release acetaminophen 650 mg two pills every eight hours regularly.~Naproxen 500mg as rescue medication if still in pain 60 minutes after treatment with acetaminophen."
Hopital du Sacre-Coeur de Montreal, Montreal
Hopital de l'Enfant-Jesus
OTHER
The Ottawa Hospital
OTHER
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
OTHER