Dexmedetomidine and Vasopressin in Septic Shock

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

260

Participants

Timeline

Start Date

June 30, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
SepsisSeptic Shock
Interventions
DRUG

DEX-PRESSIN

This group will receive vasopressin as the first-line vasopressor. DEX will be started after hemodynamic stabilization if the heart rate is \>90 beats per minute (bpm). NE infusion will be the second-line vasoactive drug.

DRUG

Standard of Care

This group will receive conventional treatment according to the SSC 2021 guidelines. This group will receive vasopressin as the second line after NE and will not receive DEX.

All Listed Sponsors
lead

Mansoura University

OTHER