Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 20, 2024

Primary Completion Date

April 16, 2025

Study Completion Date

July 15, 2025

Conditions
Acute Respiratory Failure
Interventions
DEVICE

Asymmetric High flow nasal cannula

"* Both the test group and the control group apply high flow oxygen therapy for at least 24 hours from the time of initial excretion (0h), and only the nasal interface is applied differently depending on the allocation group.~* The initial flow rate setting is 10 L/min, and it can be adjusted up to 50 L/min within the range where the subject does not experience discomfort. Except for cases where the patient complains of being hot, the initial temperature setting is 37°C, and the inhaled oxygen concentration (FiO2) may be adjusted to a target of 93% or more of peripheral oxygen saturation (SpO2) in the range of 21 to 100%.~* After 24 hours, high flow oxygen therapy is discontinued and conventional oxygen therapy can be applied if necessary."

DEVICE

Standard(symmetric) High flow nasal cannula

"* Both the test group and the control group apply high flow oxygen therapy for at least 24 hours from the time of initial excretion (0h), and only the nasal interface is applied differently depending on the allocation group.~* The initial flow rate setting is 10 L/min, and it can be adjusted up to 50 L/min within the range where the subject does not experience discomfort. Except for cases where the patient complains of being hot, the initial temperature setting is 37°C, and the inhaled oxygen concentration (FiO2) may be adjusted to a target of 93% or more of peripheral oxygen saturation (SpO2) in the range of 21 to 100%.~* After 24 hours, high flow oxygen therapy is discontinued and conventional oxygen therapy can be applied if necessary."

Trial Locations (1)

Unknown

Samsung Medical Center, Seoul

All Listed Sponsors
collaborator

Fisher and Paykel Healthcare

INDUSTRY

lead

Samsung Medical Center

OTHER

NCT06301035 - Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group | Biotech Hunter | Biotech Hunter