The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

June 15, 2025

Primary Completion Date

August 15, 2025

Study Completion Date

October 15, 2025

Conditions
Symptomatic Irreversible Pulpitis
Interventions
DRUG

Trypsin, Bromelain and Rutoside

Flamogen is a combination of trypsin 48 mgs, bromelain 90mg and rutoside 100 mg in one tablet that provides an anti inflammatory, anti edematous activity. each patient will receive a single dose of 2 tablets one hour before treatment.

DRUG

Diclofenac Potassium

Non-steroidal anti inflammatory drug. cataflam is known for its potent anti inflammatory and analgesic properties. each patient will receive one tablet of cataflam 50 mg 1 hour before treatment.

DRUG

Prednisolone Oral Tablet

Steroids are potent anti inflammatory drugs, patients are going to receive one tablet of 30 mg solupred one hour before treatment

OTHER

Placebo

A tablet of Compacted powdered milk

Trial Locations (2)

11829

RECRUITING

Faculty of Oral and Dental Medicine, Egyptian Russian University, Cairo

4450113

RECRUITING

Faculty of Dentistry, Cairo University, Cairo

All Listed Sponsors
collaborator

Egyptian Russian University

NETWORK

lead

Cairo University

OTHER

NCT06298383 - The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain | Biotech Hunter | Biotech Hunter