NCT06296173View on ClinicalTrials.gov

Open Lung Protective Extubation Following General Anesthesia

NARecruitingINTERVENTIONAL
Enrollment

270

Participants

Timeline

Start Date

October 8, 2024

Primary Completion Date

December 1, 2025

Study Completion Date

April 1, 2026

Conditions
Intra-abdominal SurgeryAnesthesiaLung InjuryVentilator-Induced Lung InjuryAtelectasis
Interventions
OTHER

"Protective open-lung extubation"

Emergence using 50% FiO2, semi-sitting position with pressure support ventilation and preserved PEEP

OTHER

Conventional extubation

Emergence using 100% FiO2, dorsal decubitus position with assistance or manual bag ventilation without PEEP

Trial Locations (4)

K1H 8L6

NOT_YET_RECRUITING

The Ottawa Hospital, Ottawa

M5B 1W8

NOT_YET_RECRUITING

Unity Health Network, Toronto

H2X 0C1

RECRUITING

Centre Hospitalier de l'Université de Montréal (CHUM), Montreal

G1V 4G2

NOT_YET_RECRUITING

CHU de Québec - Université Laval, Québec

All Listed Sponsors
collaborator

CHU de Quebec-Universite Laval

OTHER

collaborator

The Ottawa Hospital

OTHER

collaborator

University Health Network, Toronto

OTHER

collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER