Neoadjuvant Immunochemotherapy in PD-L1-negative LACC

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 12, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 12, 2030

Conditions
Cervical CancerLocally Advanced Cervical CancerPD-L1 NegativeNeoadjuvant Chemoimmunotherapy
Interventions
DRUG

Camrelizumab

200 mg, intravenously, 20-60 min. 2 times, every 21 days

DRUG

Paclitaxel-albumin

260 mg/m² over 30 min, 3 times, every 21 days

DRUG

Cisplatin

4 h, 75-80 mg/m², 3 times, every 21 days

PROCEDURE

radical surgery

Radical hysterectomy + pelvic lymphadenectomy 士 para-aortic lymphadenectomy

Trial Locations (12)

230000

RECRUITING

Anhui Provincial Cancer Hospital, Hefei

310022

RECRUITING

Women's Hospital, Zhejiang University School of Medicine, Hangzhou

RECRUITING

Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou

400038

RECRUITING

The First Affiliated Hospital (Southwest Hospital), Army Medical University (Third Military Medical University), Chongqing

410008

RECRUITING

Xiangya Hospital, Central South University, Changsha

430030

RECRUITING

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

530021

RECRUITING

The Affiliated Tumor Hospital of Guangxi Medical University, Nanning

610041

RECRUITING

Second People's Hospital of Sichuan (Sichuan Cancer Hospital), Chengdu

730050

RECRUITING

Gansu Provincial Maternity and Child-care Hospital, Lanzhou

Unknown

RECRUITING

Beiing Friendship Hospital, Capital Medical University, Beijing

RECRUITING

Shengjing Hospital of China Medical University, Shenyang

RECRUITING

Tianjin Medical University General Hospital, Tianjin

All Listed Sponsors
collaborator

Southwest Hospital, China

OTHER

collaborator

Women's Hospital School Of Medicine Zhejiang University

OTHER

collaborator

Anhui Provincial Cancer Hospital

OTHER

collaborator

Sichuan Cancer Hospital and Research Institute

OTHER

collaborator

Gansu Provincial Maternal and Child Health Care Hospital

OTHER

collaborator

Beijing Friendship Hospital

OTHER

collaborator

Tianjin Medical University General Hospital

OTHER

collaborator

Xiangya Hospital of Central South University

OTHER

collaborator

West China Second University Hospital

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

collaborator

Zhejiang Cancer Hospital

OTHER

collaborator

Shengjing Hospital

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

Cancer Hospital of Guangxi Medical University

OTHER

lead

Tongji Hospital

OTHER