CPAP in Patients With Severe Obesity After Anesthesia

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 31, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

June 30, 2026

Conditions
Obesity, AbdominalAnesthesia MorbidityApnea, Obstructive SleepAtelectases, Postoperative PulmonaryVentilator Lung
Interventions
DEVICE

Recruitment/ITP-CPAP (Intervention A)

Participant will receive a recruitment maneuver followed by CPAP set to the level of end-expiratory esophageal pressure (measured during atmospheric pressure breathing). The intervention will last for 20 minutes.

DEVICE

Standard CPAP (Intervention B)

Participant will receive their home CPAP (if on CPAP at home) or CPAP at 8-10 cmH20 (if not on CPAP at home or no known diagnosis of OSA). The intervention will last for 20 minutes.

DEVICE

Atmospheric Pressure

Participant will breathe at atmosphere pressure (no CPAP) with supplemental oxygen as needed per clinical guidance.

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT06287632 - CPAP in Patients With Severe Obesity After Anesthesia | Biotech Hunter | Biotech Hunter