The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive Functions

NANot yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

July 31, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

November 30, 2025

Conditions
Executive Function
Interventions
DIETARY_SUPPLEMENT

Short Chain Fatty Acids (SCFAs).

Colon-delivery capsules of SCFAs.

DIETARY_SUPPLEMENT

Placebo

Microcrystaline cellulose placebo capsules.

OTHER

Maastricht Acute Stress Task

The Maastricht Acute Stress Task. This 15-minute stress-inducing task consists of a 5-minute preparation phase where instructions about the upcoming tasks are given, followed by a 10-minute acute stress phase where the hand immersion trial (HIT) in ice-cold water and mental arithmetic (MA) task is given interchangeably.

OTHER

No-stress control task

The placebo version of the MAST follows the same structure of the MAST with none of the stress elements. It uses lukewarm water and simple arithmetic's.

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Universitaire Ziekenhuizen KU Leuven

OTHER

NCT06286943 - The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive Functions | Biotech Hunter | Biotech Hunter