Tirelizumab Combined With Chemotherapy in the Treatment of HER-2 Negative Locally Advanced Gastric Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

April 30, 2025

Study Completion Date

July 30, 2025

Conditions
Locally Advanced Gastric CarcinomaHER2 NegativeEfficacySafety
Interventions
DRUG

Tirolizumab+SOX/XELOX

Tirolizumab combined with chemotherapy(SOX/XELOX) regimen. The SOX regimen consists of the drugs Tegilol (S-1) and Oxaliplatin. The XELOX regimen consists of the drugs oxaliplatin and capecitabine.

DRUG

SOX/XELOX

Simple chemotherapy regimen (SOX/XELOX regimen). The SOX regimen consists of the drugs Tegilol (S-1) and Oxaliplatin. The XELOX regimen consists of the drugs oxaliplatin and capecitabine.

Trial Locations (1)

100853

RECRUITING

General Surgery Institute, China PLA General Hospital, Beijing

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Lin Chen

OTHER