A Study to Evaluate the Benefit of Adding Durvalumab After Chemotherapy, Durvalumab and Surgery in Patients With Early-stage, Operable, Non-small Cell Lung Cancer.

PHASE3RecruitingINTERVENTIONAL
Enrollment

290

Participants

Timeline

Start Date

January 15, 2025

Primary Completion Date

October 31, 2029

Study Completion Date

March 31, 2030

Conditions
Non Small Cell Lung Cancer
Interventions
DRUG

Adjuvant durvalumab

Durvalumab is given at a fixed dose of 1500 mg i.v. every 4 weeks (±1 week) until relapse or unacceptable toxicity, for a maximum of 12 cycles after surgery.

Trial Locations (42)

Unknown

NOT_YET_RECRUITING

Chris O'Brien Lifehouse, Camperdown

RECRUITING

Nepean Hospital, Penrith

RECRUITING

Royal North Shore Hospital, St Leonards

NOT_YET_RECRUITING

Princess Alexandra Hospital, Woolloongabba

NOT_YET_RECRUITING

Flinders Medical Centre, Bedford Park

NOT_YET_RECRUITING

Royal Hobart Hospital, Hobart

RECRUITING

Eastern Health, Box Hill

RECRUITING

Alfred Hospital, Melbourne

RECRUITING

Peter MacCallum Cancer Centre, Parkville

NOT_YET_RECRUITING

Sir Charles Gairdner Hospital, Nedlands

NOT_YET_RECRUITING

Wien AKH, Vienna

RECRUITING

Institut Jules Bordet - HUB, Anderlecht

NOT_YET_RECRUITING

Antwerp University Hospital, Antwerp

RECRUITING

North Estonia Medical Centre Foundation, Talinn

RECRUITING

CHU Angers, Angers

NOT_YET_RECRUITING

Institut Bergonié, Bordeaux

RECRUITING

Le Mans - CHG, Le Mans

RECRUITING

Lyon - Centre Léon Bérard, Lyon

RECRUITING

Beaumont Hospital, Dublin

NOT_YET_RECRUITING

St James's Hospital, Dublin

NOT_YET_RECRUITING

SS Antonio e Biagio e Cesare Arrigo Hospital, Alessandria

NOT_YET_RECRUITING

Istituto Oncologico Veneto, Padua

NOT_YET_RECRUITING

Perugia Hospital, Perugia

RECRUITING

"Istituto Nazionale Tumori Regina Elena", Rome

NOT_YET_RECRUITING

AOUS Policlinico Le Scotte, Siena

NOT_YET_RECRUITING

Universita di Verona - Department of Medicine, Verona

NOT_YET_RECRUITING

NKI, Amsterdam

NOT_YET_RECRUITING

UMCU, Utrecht

NOT_YET_RECRUITING

Kantonsspital Baden, Baden

RECRUITING

Universitätsspital Basel, Basel

NOT_YET_RECRUITING

Eoc - Iosi, Bellinzona

RECRUITING

Inselspital Bern, Bern

RECRUITING

HFR Hôpital Fribourgeois, Fribourg

NOT_YET_RECRUITING

CHUV, Lausanne

RECRUITING

Kantonsspital St.Gallen, Sankt Gallen

RECRUITING

Kantonsspital Winterthur, Winterthur

NOT_YET_RECRUITING

University Hospital Zurich, Zurich

RECRUITING

Barts Health NHS Trust, London

NOT_YET_RECRUITING

Royal Marsden Hospital (Chelsea), London

NOT_YET_RECRUITING

Royal Marsden Hospital (Sutton), London

RECRUITING

Maidstone and Tunbridge Wells NHS Trust, Maidstone

RECRUITING

Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

ETOP IBCSG Partners Foundation

NETWORK