Protective Anesthesiological Management Procedure Imposes Control on Respiratory Comlications

NARecruitingINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

October 10, 2023

Primary Completion Date

June 30, 2024

Study Completion Date

September 30, 2024

Conditions
Well-Being, Psychological
Interventions
PROCEDURE

The procedure of protective lung ventilation

The procedure of protective lung ventilation in the PV group of patients included preoxygenation with 60% oxygen in a mixture with air for 3 min, which maintained the target peripheral oxygen saturation at values above 94%, endotracheal intubation, volume-controlled mechanical ventilation, a tidal volume of 6 ml per kg of body weight. Normocarbia during the protective ventilation procedure was maintained by adjusting the minute ventilation, which is the product of the respiratory rate (12-14 breaths per minute) and the tidal volume set to 6 ml/kg of body weight. The most critical variable for the adjustment was the inhalation-exhalation ratio of 1:2, which ensured adequate oxygenation and removal of carbon dioxide during anesthesia. Identically as in the PV group, the target peripheral saturation was kept above 94% with an inspiratory oxygen concentration of 50% and peak airway pressure values of up to 40 kPa.

Trial Locations (1)

49210

RECRUITING

General hospital Zabok, Zabok

All Listed Sponsors
collaborator

Prof.Dinko Tonković, MD, PhD Head of Department of Anesthesiology, Reanimatology and Intensive Care Medicine and Pain Therapy, University Hospital Centre Zagreb

UNKNOWN

collaborator

Assist. Prof. Slavica Sović, MD, PhD Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Štampar

UNKNOWN

collaborator

Prof. Goran Šimić, MD, PhD Professor of Neuroscience and Anatomy, Chair, Department of Neuroscience, Croatian Institute for Brain Research, University of Zagreb

UNKNOWN

collaborator

Prof. Anamarija Jazbec, Faculty of Forestry and Wood Technology, University of Zagreb

UNKNOWN

collaborator

Marijan Jedvaj, MD Anesthesiologist and ICU physician (Consultant), Head of Department of Anesthesia and IC, General Hospital Zabok

UNKNOWN

lead

Masa Kontic

OTHER_GOV