Selected Immunological Indicators and Microbiota in Patients With Premature Birth and Preeclampsia

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2023

Primary Completion Date

March 30, 2025

Study Completion Date

March 30, 2025

Conditions
Preterm BirthPreeclampsia
Interventions
DIAGNOSTIC_TEST

Peripheral blood collection

"The phenotypic characteristics of leukocytes will be compared between the groups to identify immunological markers of women at risk of preterm delivery.~Samples from the controls will be taken to define a baseline for the measured leukocyte populations."

DIAGNOSTIC_TEST

Swab sample collection

Oral, vaginal and rectal swabs will be collected and stored for analysis of microbiota at the time of inclusion. At birth, oral, vaginal and rectal swabs and part of the placenta (placental tissue) will be collected for further analysis.

Trial Locations (1)

128 08

RECRUITING

Department of Gynaecology, Obstetrics and Neonatology of the First Faculty of Medicine of the Charles University and General University Hospital in Prague, Prague

All Listed Sponsors
collaborator

Charles University, Czech Republic

OTHER

collaborator

Institute of Hematology and Blood Transfusion, Czech Republic

OTHER

lead

General University Hospital, Prague

OTHER