NCT06278727View on ClinicalTrials.gov

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

RecruitingOBSERVATIONAL
Enrollment

270

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

June 1, 2025

Study Completion Date

December 31, 2025

Conditions
Mitral RegurgitationHeart Failure
Interventions
DRUG

angiotensin-converting enzyme inhibitors/angiotensin II receptor blocker/angiotensin receptor-neprilysin inhibitor

Guideline-directed Medical Therapy (GDMT) includes those 4 drugs, and only taking at least 3 drugs could be recognized as GDMT.

OTHER

The development of the prediction model

The prediction model of FMR regression would be developed to recognize patients whose FMR would regress due to GDMT, and consequently help determine the treatment.

Trial Locations (1)

Unknown

RECRUITING

Sun-Yatsen Memorial Hospital, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER