21
Participants
Start Date
April 30, 2024
Primary Completion Date
January 31, 2026
Study Completion Date
January 31, 2027
Acute Intermittent Hypoxia
During each AIH session, the participant will be equipped with a non-rebreathing face mask, and provided with the AIH intervention. The AIH intervention involves alternating breathing cycles: one with lower oxygen concentration (9-10% Oxygen) than that at sea level (\~21% Oxygen) lasting between 30 and 60 seconds, followed by a similar duration of normal room air (21% Oxygen). This cycle will be repeated 15 times in one session, continuous blood oxygen levels and heart rate will be monitored.
Sham-Acute Intermittent Hypoxia
During each Sham-AIH session, the participant will be equipped with a non-rebreathing face mask, and provided with the Sham-AIH intervention. The Sham-AIH intervention involves alternating breathing cycles: both with oxygen concentrations of \~21% Oxygen lasting between 30 and 60 seconds, followed by another similar duration of normal room air (21% Oxygen). This cycle will be repeated 15 times in one session, continuous blood oxygen levels and heart rate will be monitored.
RECRUITING
Shirley Ryan AbilityLab, Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Northwestern University
OTHER
Shirley Ryan AbilityLab
OTHER