NCT06274541View on ClinicalTrials.gov

Upfront Systematic Tumour BRCA Testing in Patients With High Grade Serous or Endometrioid Ovarian, Fallopian Tube or Primary Peritoneal Cancer (HGSEC): The t-BRCA Study

Active, not recruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

March 22, 2019

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Serous Ovarian TumorEndometrioid Carcinoma OvaryFallopian Tube CancerPrimary Peritoneal Carcinoma
Interventions
GENETIC

Somatic and Germline BRCA1/2 Testing

Germline BRCA1/2 mutation testing will be undertaken by NGS using blood samples. Somatic BRCA1/2 mutation testing will be undertaken by NGS using tumour tissue.

Trial Locations (5)

Unknown

Mater Misericordiae University Hospital / Mater Private Hospital, Dublin

St James's Hospital, Dublin

Bon Secours, Cork

Cork University Hospital, Cork

University Hospital Limerick, Limerick

All Listed Sponsors
lead

Cancer Trials Ireland

NETWORK