The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

RecruitingOBSERVATIONAL
Enrollment

225

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2028

Conditions
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme of BrainAstrocytoma, MalignantBrain NeoplasmsBrain Neoplasms, Adult, MalignantBrain Neoplasms, AdultRecurrent Adult Brain TumorRecurrent Glioblastoma
Interventions
PROCEDURE

Awake mapping under local anesthesia

During an awake craniotomy, the patient is awake and cooperative during the resection of the tumor while the surgeon uses electro(sub)cortical mapping to prevent damage to eloquent areas.

PROCEDURE

Asleep mapping under general anesthesia

During asleep mapping under general anesthesia, the surgeon uses electro(sub)cortical mapping with evoked potentials (MEPs, SSEPs or continuous dynamic mapping) to prevent damage to eloquent areas.

PROCEDURE

Resection under general anesthesia without mapping

During resection under general anesthesia without mapping, the surgeon does not use any intraoperative stimulation mapping techniques to identify eloquent areas.

Trial Locations (8)

94143

RECRUITING

University of California, San Francisco, San Francisco

02114

RECRUITING

Massachusetts General Hospital, Boston

Unknown

RECRUITING

University Hospital Leuven, Leuven

RECRUITING

Universitätsklinikum Heidelberg, Heidelberg

NOT_YET_RECRUITING

Technical University Munich, Munich

RECRUITING

Haaglanden Medical Center, The Hague

NOT_YET_RECRUITING

Inselspital Universitätsspital Bern, Bern

3015 GD

RECRUITING

Erasmus Medical Center, Rotterdam

Sponsors
All Listed Sponsors
collaborator

Haaglanden Medical Centre

OTHER

collaborator

Universitaire Ziekenhuizen KU Leuven

OTHER

collaborator

University Hospital Heidelberg

OTHER

collaborator

Technical University of Munich

OTHER

collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

University of California, San Francisco

OTHER

lead

Erasmus Medical Center

OTHER