NCT06271564View on ClinicalTrials.gov

Effectiveness of Topical Magnetite Zinc Oxide Composite Nanoparticles in the Management of Oral Potentially Malignant Lesions

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 29, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Oral Potentially Malignant Lesions
Interventions
DRUG

Magnetite ZnO Composite Nanoparticles

Magnetite ZnO-Fe3O4 conjugated NPs retained inherent selective property of ZnO and magnetic property of Fe3O4 NPs and showed preferential cytotoxicity towards breast cancer cell line MDA-MB-231, with no significant cytotoxicity towards noncancerous Mouse Fibroblast NIH 3T3 cell

DRUG

Topical Placebo Gel

Topical placebo gel containing water, glycerin and Hydroxypropyl methylcellulose will be applied 3 times daily for 6 weeks as a positive control group

Trial Locations (1)

Unknown

RECRUITING

Faculty of Dentistry Ain shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER