A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR)

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

255

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Diabetic Retinopathy
Interventions
DRUG

Tarcocimab

Intravitreal injection

OTHER

Sham injection

The sham injection is a procedure that mimics an intravitreal injection. It involves pressing the blunt end of an empty syringe (without a needle) against the anesthetized eye. It is performed to maintain masking of the study.

Trial Locations (38)

16507

Erie Retina Research, Erie

21740

Cumberland Valley Retina Consultants, Hagerstown

24502

Piedmont Eye Center, Lynchburg

27511

North Carolina Retina Associates (Cary), Cary

27587

North Carolina Retina Associates (Wake Forest), Wake Forest

28803

Asheville Eye Associates, Asheville

29414

Charleston Neuroscience Institute, Charleston

30909

Southeast Retina Center, Augusta

33308

Retina Group of Florida, Fort Lauderdale

33880

Center for Retina and Macular Disease, Winter Haven

37922

Southeastern Retina Associates PC, Knoxville

38138

Charles Retina Institute, Germantown

46290

Associated Vitreoretinal and Uveitis Consultants, Carmel

62703

Springfield Clinic LLP, Springfield

75075

Texas Retina Associates, Plano

76028

Star Vision Research, Burleson

77384

Retina Consultants of Texas (Woodlands), The Woodlands

77401

Retina Consultants of Texas (Bellaire), Bellaire

77494

Retina Consultants of Texas (Katy), Katy

78240

Retina Consultants of Texas (San Antonio), San Antonio

78681

Austin Retina Associates, PLLC (Round Rock), Round Rock

78705

Austin Research Center for Retina, Austin

79106

Panhandle Eye Group, LLP. - Southwest Retina Specialists, Amarillo

79606

Retina Research Institute of Texas, Abilene

85704

Retina Associates SW, Tucson

89052

Retina Consultants of Nevada, Henderson

91204

Global Research Management, Inc. - Lugene Eye Institute, Glendale

92374

Retina Consultants of Southern California, Redlands

92835

Retina Consultants of Orange County, Fullerton

95356

Retinal Consultants Medical Group, Inc., Modesto

95825

Retinal Consultants Medical Group, Inc., Sacramento

97477

Cascade Medical Research Institute, Springfield

98004

Pacific Northwest Retina (Bellevue), Bellevue

99204

Spokane Eye Clinical Research, Spokane

06385

Retina Group of New England, PC, Waterford

07003

Envision Ocular, LLC, Bloomfield

78705-1169

Austin Retina Associates, PLLC (Austin), Austin

00612

Emanuelli Research & Development Center, LLC, Arecibo

Sponsors
All Listed Sponsors
lead

Kodiak Sciences Inc

INDUSTRY

NCT06270836 - A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer Compared With Sham Treatment in Participants With Diabetic Retinopathy (DR) | Biotech Hunter | Biotech Hunter