Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate

NANot yet recruitingINTERVENTIONAL
Enrollment

14,000

Participants

Timeline

Start Date

April 30, 2025

Primary Completion Date

April 30, 2029

Study Completion Date

April 30, 2029

Conditions
Renal FailureHemodialysis
Interventions
OTHER

Bicarbonate

Bicarbonate is added to hemodialysis fluids to correct the metabolic acidosis that arises from kidney failure. Some dialysis units in Canada add bicarbonate to a level of 32 mmol/L, while other units add bicarbonate to a level of 38 mmol/L. It is unknown whether one level is better for people's health.

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

ACT

UNKNOWN

lead

McMaster University

OTHER

NCT06270134 - Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate | Biotech Hunter | Biotech Hunter