Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias

NARecruitingINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

March 31, 2027

Conditions
Autosomal Recessive Spastic Ataxia of Charlevoix-SaguenaySpastic Paraplegia 7
Interventions
PROCEDURE

IMPACT - rehabIlitation prograM for sPAstiC aTaxias

The rehabilitation program will last 12 weeks and consists of three training sessions of 60 minutes per week (2 sessions in a therapy room and 1 session in an adapted pool with multiple levels of water) for a total of 36 sessions. Participants will be divided into 7 subgroups of 6 participants and each sub-group will be supervised by one physiotherapist (PT) and one physiotherapy technologist for safety considerations. It will focus on these three domains: 1) postural control; balance, trunk-limbs and multi-joints control and coordination and 3) functional mobility. Each domain contains a standardized list of exercises with different difficulty levels and specific times allocation. All exercises will be executed by the participants at each session at the appropriate difficulty level. The initial level of difficulty for each exercise will be determined by the PT based on individual results of the pre-intervention assessment and on individual performance, fatigue level and safety.

Trial Locations (5)

G3Z 0K3

NOT_YET_RECRUITING

CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul, Baie-Saint-Paul

G5A 1T1

NOT_YET_RECRUITING

CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie, La Malbaie

H2H 2N8

RECRUITING

CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau, Montreal

G1M 2S8

RECRUITING

CIUSSS de la Capitale-Nationale, installation IRDPQ, Québec

G7X 7X2

RECRUITING

Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière, Saguenay

All Listed Sponsors
collaborator

McGill University

OTHER

collaborator

Université de Sherbrooke

OTHER

collaborator

Université du Québec a Montréal

OTHER

collaborator

Laval University

OTHER

collaborator

University of Calgary

OTHER

collaborator

Corporation de recherche et d'action sur les maladies héréditaires (CORAMH)

UNKNOWN

collaborator

Cégep de Jonquière

UNKNOWN

collaborator

Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean

UNKNOWN

collaborator

Muscular Dystrophy Canada

OTHER

collaborator

University of Alberta

OTHER

collaborator

Integrated University Health and Social Services Center of the Capitale-Nationale

OTHER

lead

Université du Québec à Chicoutimi

OTHER