Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

July 23, 2024

Primary Completion Date

October 29, 2026

Study Completion Date

October 29, 2026

Conditions
Anatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor-Positive Breast CarcinomaMetastatic Breast Carcinoma
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Bone Scan

Undergo bone scan

PROCEDURE

Computed Tomography

Undergo PET/CT scan

DRUG

F-18 16 Alpha-Fluoroestradiol

Given IV

PROCEDURE

Positron Emission Tomography

Undergo PET/CT scan

OTHER

Questionnaire Administration

Ancillary studies

RADIATION

Stereotactic Body Radiation Therapy

Undergo SBRT

Trial Locations (2)

91010

RECRUITING

City of Hope Medical Center, Duarte

92618

RECRUITING

City of Hope at Irvine Lennar, Irvine

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

City of Hope Medical Center

OTHER