TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children

PHASE3RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 17, 2024

Primary Completion Date

May 31, 2027

Study Completion Date

May 31, 2028

Conditions
Rheumatic FeverSydenham Chorea
Interventions
DRUG

Dexamethasone Oral

Dexamethasone suspension (1mg/ml) 20mg/m2/day (maximum dose 24mg/day) given in three divided doses

DRUG

Placebo

Matching capsules taken orally three times daily for three days

Trial Locations (17)

0810

RECRUITING

Royal Darwin Hospital, Darwin

Unknown

RECRUITING

KidzFirst Hospital, Auckland

RECRUITING

Starship Child Health, Te Toka Tumai, Auckland, Auckland

RECRUITING

Waitākere Hospital, Auckland

RECRUITING

Gisborne Hospital, Gisborne

RECRUITING

Waikato Hospital, Hamilton

RECRUITING

Hawkes Bay Fallen Soldiers' Memorial Hospital, Hastings

RECRUITING

Hutt Hospital, Lower Hutt

RECRUITING

Wairarapa Hospital, Masterton

RECRUITING

Taranaki Base Hospital, New Plymouth

RECRUITING

Palmerston North Hospital, Palmerston North

RECRUITING

Rotorua Hospital, Rotorua

RECRUITING

Tauranga Hospital, Tauranga

RECRUITING

Wellington Regional Hospital, Wellington

RECRUITING

Whakatāne Hospital, Whakatāne

RECRUITING

Whanganui Hospital, Whanganui

RECRUITING

Whangārei Hospital, Whangarei

All Listed Sponsors
collaborator

Health Research Council, New Zealand

OTHER

collaborator

Menzies School of Health Research

OTHER

lead

Starship Child Health, Te Toka Tumai Auckland

OTHER_GOV