Recruitment Maneuver in General Anesthesia for Laparoscopic Cholecystectomy

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

February 1, 2025

Study Completion Date

September 1, 2025

Conditions
Mechanical Ventilation Pressure High
Interventions
PROCEDURE

Recruitment maneuver

The recruitment maneuver will be performed by increasing the current peak pressure (Ppeak) by 5 cm H2O, changing the inspiratory/expiratory ratio from 1:2 to 1:1, with PEEP values of 5 and 7 cm H2O. The respiratory rate during the recruitment maneuver will be 10 breaths per minute, and the recruitment maneuver will last 30 seconds (5 breaths). The recruitment maneuver will be performed 3 times: the first time immediately after the formation of the pneumoperitoneum and the positioning of the patient in the reverse Trendelenburg position with a PEEP of 5 cm H2O, the second time with a PEEP of 7 cm H2O, during the duration of the operation. The third recruitment maneuver will be performed with a PEEP of 7 cm H2O at the end of the operative procedure, and immediately before the patient wakes up. After each increase, PEEP will be maintained at higher pressure values with a peak value of 7 cm H2O.

Trial Locations (1)

21000

RECRUITING

Clinical center of Vojvodina, Novi Sad

All Listed Sponsors
lead

University of Novi Sad

OTHER