Effect of Peripheral VA-ECMO Flow Variations on the Pulmonary Arterial Occlusion Pressure (PAPO) in Patients With Refractory Cardiogenic Shock.

NACompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

March 7, 2024

Primary Completion Date

January 13, 2025

Study Completion Date

January 13, 2025

Conditions
Cardiogenic Shock
Interventions
OTHER

ECMO-Flow variations

"The protocol unfolds in 5 steps as follows, each step lasting between 10 and 15 minutes to allow for the patient's hemodynamic adaptation. At each step, invasive and non-invasive hemodynamic evaluation is performed.~1. The 1st step is called 100% flow: it involves recording the patient's hemodynamic measurements at the baseline, i.e., at 100% of their ECMO-VA flow, previously set by the clinician entirely independently of the study.~2. The 2nd step is called 125% flow: the patient's ECMO-VA flow is increased to 125% of the initial flow.~3. The 3rd step is called 150% flow: the patient's ECMO-VA flow is increased to 150% of the initial flow.~4. The 4th step is called 175% flow: the patient's ECMO-VA flow is increased to 175% of the initial flow.~5. The 5th and final step is called 200% flow: the patient's ECMO-VA flow is increased to 200% of the initial flow."

Trial Locations (1)

75013

Service de réanimation médicale, Hôpital Pitié-Salpêtrière,, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER