Left Roof Linear, Mitral Isthmus Linear and Left Anterior Septal Linear Ablation for Non-paroxysmal AF: PROMISED Trial.

NARecruitingINTERVENTIONAL
Enrollment

166

Participants

Timeline

Start Date

January 28, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Atrial FibrillationAtrial Fibrillation, Persistent
Interventions
PROCEDURE

PROMISED

CPVI: Achievement of a wide disconnection of the right and left pulmonary veins; Roof linear ablation: linear ablation in the left atria roof; Anterior septal linear ablation: linear ablation in the anterior septal linear which coursed from the middle of the right superior and inferior pulmonary veins or the middle of the right superior pulmonary vein to the mitral valve annulus; Mitral isthmus linear ablation: linear ablation in the mitral isthmus; Left atrial appendage closure: Occlusion of the left atrial appendage with a left atrial appendage occlusion device.

PROCEDURE

CPVI and LAAC

CPVI: Achievement of a wide disconnection of the right and left pulmonary veins; Left atrial appendage closure: Occlusion of the left atrial appendage with a left atrial appendage occlusion device.

DEVICE

Radiofrequency ablation catheter

Device: Radiofrequency ablation catheter

DEVICE

left atrial appendage occlusion device

Device: left atrial appendage occlusion device

Trial Locations (1)

325000

RECRUITING

Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou

All Listed Sponsors
lead

Second Affiliated Hospital of Wenzhou Medical University

OTHER