The Safety and Efficacy of Autologous Transfusion in Spinal Surgery for Lung Cancer With Spinal Metastasis

NARecruitingINTERVENTIONAL
Enrollment

118

Participants

Timeline

Start Date

March 15, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2027

Conditions
Spinal MetastasesBlood Transfusion ComplicationLung CancerSurgeryAutologous Blood Transfusion
Interventions
PROCEDURE

Autoblood transfusion

Through a negative pressure suction device, the patient's blood that flows out during surgery is collected into a blood storage filter. During the suction process, it is mixed with an appropriate anticoagulant and passed through multiple layers of filters. When the volume of recovered blood reaches a certain level, it is continuously (or intermittently) centrifuged. Using a high-speed centrifugal blood recovery tank, the red blood cells are separated, and the plasma, waste, cell fragments, anticoagulants, and harmful components are diverted into a waste bag. A large amount of saline is used to repeatedly wash, purify, and concentrate the red blood cells. Finally, the concentrated red blood cells are prepared into a 70% red blood cell suspension with saline and stored in a collection bag for transfusion back to the patients. Open surgery is considered as the standard procedure for metastatic spinal cord compression

Trial Locations (1)

516008

RECRUITING

Guangdong provincial people's hospital, Guangzhou

All Listed Sponsors
lead

Guangdong Provincial People's Hospital

OTHER