NCT06242236View on ClinicalTrials.gov

Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)

NACompletedINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

October 31, 2024

Study Completion Date

June 30, 2025

Conditions
ARDSRespiratory EffortMechanical Ventilation ComplicationSedation
Interventions
OTHER

The respiratory effort parameters guide sedative dosage.

The intervention involves the measurement of respiratory effort using P0.1 and Pocc then calculating to dynamic transpulmonary pressure swing (Predicted ΔPL) to adjust sedative drug dosage.

Trial Locations (1)

10400

Critical care medicine Ramathibodi hospital, 270 Rama 6 Rd. Phayatai, Ratchathewi

All Listed Sponsors
lead

Ramathibodi Hospital

OTHER

NCT06242236 - Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2) | Biotech Hunter | Biotech Hunter