Mesenteric Surgical Margin for Crohn's Disease Endoscopic Recurrence

NARecruitingINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2031

Conditions
Endoscopic Recurrence RateAfter Ileocolic Crohn 's Disease Surgery
Interventions
PROCEDURE

mesentery-guided resection margin

Mesentery-guided resection margin where the mesentery adjacent to the intestine completely transitions from abnormal to normal upon palpation and transillumination, compared to the proximal normal mesentery. Open, laparoscopic, hand-assisted, or robotic mobilization are all acceptable, but extracorporeal resection and anastomosis are required. After intestinal mobilization , the diseased intestinal segment is exteriorized from the abdominal cavity.

PROCEDURE

traditional resection margin

"2 cm proximal to the site where gross lesions disappear. After transecting the bowel, re-examine the mucosal condition; if mucosal ulcers or obvious scars are present, extend the incision until reaching the site with normal mucosa. Definition of gross lesions: Evaluation from the outer intestinal wall: The site where the tough texture, thickening, or contracture at the mesenteric edge of the intestinal wall disappears; evaluation from the intestinal lumen: The site where mucosal ulcers, fissures, or obvious scars disappear. Mucosa appearing seemingly abnormal is considered normal."

Trial Locations (1)

510000

RECRUITING

Jia Ke, Guangzhou

All Listed Sponsors
collaborator

Jinling Hospital, China

OTHER

collaborator

Sir Run Run Shaw Hospital

OTHER

collaborator

Zhongnan Hospital

OTHER

lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

NCT06241170 - Mesenteric Surgical Margin for Crohn's Disease Endoscopic Recurrence | Biotech Hunter | Biotech Hunter