Threat Reversal Abnormality in Patients With Anxiety Disorders

NANot yet recruitingINTERVENTIONAL
Enrollment

190

Participants

Timeline

Start Date

March 31, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Anxiety DisorderAnxiety State
Interventions
DEVICE

Active repetitive deep transcranial magnetic stimulation (dTMS)

"Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is accurately delivered to the intended target by an optic navigation and a deep pulse protocol at 90% of the tested threshold for 15-minute stimulation duration."

DEVICE

Sham repetitive deep transcranial magnetic stimulation (dTMS)

"Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is placed on the scalp to mimic the sensation and sounds of the actual treatment but without letting the magnetic field reach the brain tissue for 15-minute duration."

All Listed Sponsors
collaborator

The National Natural Science Foundation of China (NSFC)

UNKNOWN

lead

Shenzhen Kangning Hospital

OTHER

NCT06232369 - Threat Reversal Abnormality in Patients With Anxiety Disorders | Biotech Hunter | Biotech Hunter