190
Participants
Start Date
March 31, 2024
Primary Completion Date
September 30, 2025
Study Completion Date
September 30, 2025
Active repetitive deep transcranial magnetic stimulation (dTMS)
"Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is accurately delivered to the intended target by an optic navigation and a deep pulse protocol at 90% of the tested threshold for 15-minute stimulation duration."
Sham repetitive deep transcranial magnetic stimulation (dTMS)
"Before the intervention, the brain structure of each participant will be captured using an MRI scanner, and individualized spatial coordinates of the hypothesized target will be determined based on these 3D structural images. Then the resting motor threshold will be tested using the method of thumb twitching observation.~The intervention will employ the H7 coil that is placed on the scalp to mimic the sensation and sounds of the actual treatment but without letting the magnetic field reach the brain tissue for 15-minute duration."
The National Natural Science Foundation of China (NSFC)
UNKNOWN
Shenzhen Kangning Hospital
OTHER