Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 20, 2024

Primary Completion Date

October 1, 2024

Study Completion Date

October 1, 2024

Conditions
Atrophy, DisuseMuscle AtrophyMuscular Disorders, AtrophicDisuse AtrophyDisuse Atrophy Muscle of Thigh
Interventions
OTHER

Unilateral leg immobilization

Participants will have one leg immobilized using a rigid knee brace. Participants will be expected to keep the knee brace on for 5 days and remain non-weight bearing on the immobilized leg. Participants will use crutches to remain non-weight bearing on the immobilized leg.

OTHER

Contralateral active leg

One leg will remain non-immobilized and active during the study. Participants will use this leg to walk with crutches.

Trial Locations (1)

01760

US Army Research Institute of Environmental Medicine, Natick

All Listed Sponsors
lead

United States Army Research Institute of Environmental Medicine

FED

NCT06228742 - Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse | Biotech Hunter | Biotech Hunter