100
Participants
Start Date
April 10, 2024
Primary Completion Date
January 31, 2027
Study Completion Date
January 31, 2027
Muscle ultrasound with surface electromyography and dynamometry
The three procedures are conducted simultaneously for upper and lower extremity muscles. A standard muscle ultrasound preset with a fixed depth of 4 cm or 6 cm will be used, depending on which muscle is visualized in accordance with our routine clinical protocols. During the dynamic approach, the transducer will be placed in a longitudinal fixed position on the muscle using a ProbeFix. All measured contractions in the different muscles will be recorded as short ultrasound videos.
MRI scan
In Stage II, all patients and 10 healthy participants will undergo MRI. During the MRI procedure, we evaluate muscle fat fraction, muscle contractile volume, muscle inflammation and edema.
RECRUITING
Radboud university medical center, Nijmegen
Solve FSHD
UNKNOWN
Radboud University Medical Center
OTHER