A Trial of Selinexor, Ruxolitinib and Methylprednisolone

Selinexor (KPT-330) is a first-in-class, oral selective exportin 1 (XPO1) inhibitor (1,2). Selinexor functions by binding with and inhibiting the nuclear export protein XPO1 (also called CRM1), leading to the accumulation of tumor suppressor proteins in t

elective inhibitor of Janus kinase (JAK)

Glucocorticoid, steroid