Effectiveness of Focal Therapy in Men With Prostate Cancer

NARecruitingINTERVENTIONAL
Enrollment

356

Participants

Timeline

Start Date

February 1, 2024

Primary Completion Date

August 31, 2029

Study Completion Date

February 28, 2031

Conditions
Prostate CancerProstate Neoplasm
Interventions
PROCEDURE

Focal therapy

"Focal therapy selectively treats a specific part of the prostate while preserving the rest of the gland in men with prostate cancer.~Focal therapy with ultrasound ablation (HIFU/TULSA) or irreversible electroporation (IRE) followed by an intensive MRI follow-up scheme at 12, 24, 36, 48 and 60 months, prostate biopsy at 12 months (and also when indicated) and PSA monitoring"

PROCEDURE

Usual care

standard radical treatment; prostatectomy or radiotherapy with follow-up according international guidelines (PSA monitoring and imaging when indicated).

Trial Locations (5)

6525GA

RECRUITING

Radboud University Medical Centre, Nijmegen

Unknown

NOT_YET_RECRUITING

Hifu kliniek, Etten-Leur

NOT_YET_RECRUITING

Amsterdam UMC, Amsterdam

NOT_YET_RECRUITING

Isala klinieken, Zwolle

NOT_YET_RECRUITING

St. Antonius hospital, Nieuwegein

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Isala

OTHER

collaborator

Amsterdam UMC, location VUmc

OTHER

collaborator

St. Antionius Hospital

UNKNOWN

collaborator

Hifu kliniek

UNKNOWN

collaborator

Dutch National Health Care Institute

OTHER

collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

collaborator

Nederlandse Vereniging voor Radiotherapie en Oncologie

UNKNOWN

collaborator

Wetenschapscommissie interventieradiologie/Nederlandse vereniging voor interventieradiologie

UNKNOWN

collaborator

Inspire2live

UNKNOWN

collaborator

Prostaatkankerstichting

UNKNOWN

collaborator

Nederlandse Vereniging voor Urologie

UNKNOWN

lead

Radboud University Medical Center

OTHER

NCT06223295 - Effectiveness of Focal Therapy in Men With Prostate Cancer | Biotech Hunter | Biotech Hunter