Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

PHASE1RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 7, 2024

Primary Completion Date

January 31, 2026

Study Completion Date

August 31, 2028

Conditions
Ductal Carcinoma in Situ
Interventions
BIOLOGICAL

MUC1 Peptide Vaccine

MUC1, a therapeutic vaccine, is a transmembrane glycoprotein and a member of the mucin family of molecules.

DRUG

Hiltonol®

A synthetic dsRNA viral mimic and host-defense activator, mimics nature by combining the essential elements of human immunity.

DRUG

Aromatase Inhibitor

A type of hormone therapy for cancer used to inhibit aromatase to treat a hormone-related breast cancer.

Trial Locations (1)

15213

RECRUITING

UPMC Magee Womens Hospital, Pittsburgh

Sponsors
All Listed Sponsors
collaborator

A Glimmer of Hope Foundation

UNKNOWN

collaborator

Breast Cancer Research Foundation

OTHER

lead

Finn, Olivera, PhD

OTHER