The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC).

Pyrotinib 400mg qd po continuously

For Trastuzumab, the loading dose for the first treatment cycle is 8 mg/kg, and for subsequent cycles, 6 mg/kg. It is to be used once every three weeks

Taxanes: Usual clinical dose is administered, in a 21-day cycle.

Capecitabine: 650mg/m2 each time, given twice daily